Radiation Therapy Are Ineffective Mesothelioma Patients, However Genetic Therapy May Be a Hope
Doctors who specialize in cancer treatment determine what type of treatment to pursue for a patient. There are many options. There exists no universal treatment option for mesothelioma patients. This is due to the cancers high mortality rate, rareness, low treatment success rate, and small number of studies to provide meaningful statistics.
Mesothelioma patients have historically had a bleak outlook, but doctors have recently made progress. Traditional treatments for cancer are surgery (removing the tumor and surrounding tissue), radiation (killing the cancerous cells with radiation), and chemotherapy (poisoning the cancerous cells.) All three methods have problems. Patients with mesothelioma have not responded well to traditional radiation therapy. Researchers are looking for ways of aiming radiation directly at the tumor in hopes that this will result in less damage to healthy tissue.
Surgery takes out the mesothelial cancerous tissue around the tumor. It is a grueling surgery with unknown benefits to patients. The usual chemotherapy cocktails effective on other cancers are not effective on mesothelioma, and different combinations of chemotherapy drugs have been tried without a lot of success. Similar to radiation, focus in research is focusing on treating the physical location of the tumor with emphasis on the pleural cavity.
The high-mortality rate for mesothelioma patients means cutting-edge techniques for cancer are tried out. These techniques include a biologic therapy called the agent interleukin 2 and anti-angiogenesis drugs like thalidomide. Pemetrexed (Alimta) is a new drug that has shown results in extending life.
Considered by oncologists is where the tumor is located, what stage the mesothelioma is in, and the age and health of the patient. Two therapies that are extremely cutting-edge in fighting cancer are called photodynamic and gene therapy. Clinical trials using these techniques are being offered to some of those who have mesothelioma.
